Open AccessNatural T Regulatory Cells (n Treg) in the Peripheral Blood of Healthy Subjects and Subjects with Chronic Periodontitis – A Pilot Study
Author(s) -
Ram Sabarish,
Vittal Rao,
Lavu
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/15449.7446
Subject(s) - foxp3 , medicine , chronic periodontitis , periodontitis , il 2 receptor , regulatory t cell , pathogenesis , immunology , peripheral blood , immune system , flow cytometry , t cell
The T cells play a central role in the aetiopathogenesis of periodontal disease. Natural T regulatory cells (nTreg) are the key stone immunoregulatory elements having an anergic phenotype and play an important role in the suppression of exaggerated immune responses thereby maintaining homeostasis. There are increasing evidences for the role of nTreg in the periodontal disease pathogenesis.