Open AccessChloramphenicol – A Potent Armament Against Multi-Drug Resistant (MDR) Gram Negative Bacilli?
Author(s) -
Shilpa Sood
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/14989.7167
Subject(s) - chloramphenicol , antibiotics , microbiology and biotechnology , multiple drug resistance , medicine , antimicrobial , bacilli , gram negative bacteria , drug resistance , bacteria , streptomycin , biology , escherichia coli , biochemistry , genetics , gene
Multidrug-resistant gram-negative bacteria cause infections which are hard to treat and cause high morbidity and mortality. Due to limited therapeutic options there is a renewed interest upon older antimicrobials which had fallen into disuse as a result of toxic side effects. One such antibiotic is chloramphenicol which was sidelined due to reports linking its use with the development of aplastic anaemia.