Open AccessCorrelation of Endothelial Nitric Oxide Synthase Gene Polymorphism (GG, TT and GT Genotype) with Proteinuria and Retinopathy in Type 2 Diabetic Patients
Author(s) -
Ali Momeni,
Morteza Hashemzadeh Chaleshtori,
Saeed Saadatmand,
Soleiman Kheiri
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/14975.7291
Subject(s) - proteinuria , medicine , enos , diabetic nephropathy , retinopathy , genotype , creatinine , diabetes mellitus , nephropathy , endocrinology , diabetic retinopathy , gene polymorphism , type 2 diabetes , gastroenterology , blood urea nitrogen , nitric oxide synthase , nitric oxide , biology , kidney , gene , genetics
Nephropathy is the most important leading cause of end stage renal failure in type 2 diabetic patients, so numerous studies were done to diagnose and evaluate risk factors of diabetic nephropathy (DN). Some gene polymorphisms may be associated with progression or regression of DN, so the aim of this study was to compare prevalence of eNOS gene polymorphism in diabetic patients with controls and its association with diabetic nephropathy.