Open AccessPeriostin - A Novel Systemic Biomarker for Eosinophilic Airway Inflammation: A Case Control Study
Author(s) -
Viswanathan Emprm,
Muhasaparur Ganesan Rajanandh,
A.D. Nageswari
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/14553.7166
Subject(s) - periostin , medicine , biomarker , asthma , sputum , eosinophilic , spirometry , eosinophil , immunology , pulmonary function testing , inflammation , matricellular protein , systemic inflammation , gastroenterology , pathology , tuberculosis , biochemistry , chemistry , extracellular matrix , biology , microbiology and biotechnology
Chronic airway inflammation and remodelling are fundamental features of asthma. The molecular phenotypes in asthma are Th2 high and Th2 low. Serum periostin is a biomarker which aid in understanding Th2 high eosinophilic asthma.