Open AccessCan Panton Valentine Leukocidin Gene And Clindamycin Susceptibility Serve As Predictors of Community Origin of Mrsa From Skin and Soft Tissue Infections?
Author(s) -
Nandita Shashindran,
N. Nagasundaram,
Devinder Mohan Thappa,
Sujatha Sistla
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/14531.7036
Subject(s) - leukocidin , panton–valentine leukocidin , clindamycin , sccmec , microbiology and biotechnology , staphylococcus aureus , staphylococcal skin infections , methicillin resistant staphylococcus aureus , biology , virology , medicine , antibiotics , genetics , bacteria
Community associated Methicillin-resistant Staphylococcus aureus (CA-MRSA) strains have begun to replace Hospital Associated MRSA (HA-MRSA) strains in hospital settings all over the world. With the epidemiological distinctions between these strains beginning to become ill-defined, the categorisation of a strain as CA-MRSA or HA-MRSA is dependent on molecular methods to detect the presence of SCCmec (Staphylococcal Cassette Chromosome mec) elements. However other markers like the presence of Panton Valentine Leukocidin toxin (pvl) genes or Clindamycin susceptibility may also be associated with community origin of MRSA.