Open AccessQuantitative Assessment of Tumor Associated Macrophages in Head and Neck Squamous Cell Carcinoma Using CD68 Marker: An Immunohistochemical Study
Author(s) -
Neeta Bagul,
Souparna Roy,
Anjali P Ganjre,
Rahul Kathariya,
Aishwarya Meher,
Pratibha Singh
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/13924.7670
Subject(s) - cd68 , immunohistochemistry , pathology , tumor associated macrophage , oral mucosa , biopsy , medicine , head and neck squamous cell carcinoma , staining , stroma , cancer , tumor microenvironment , head and neck cancer
Oral Squamous Cell Carcinoma (OSCC) is one of the most prevalent cancers in India. Clear evidence regarding inflammation being an etiological factor of cancer was found only in the last few decades. A major inflammatory component in the tumor tissue is Tumor-Associated Macrophages (TAMs). The CD68 antibody is a marker for staining TAMs.