Open AccessGiant Cell Lesions of Lungs: A Histopathological and Morphometric Study of Seven Autopsy Cases
Author(s) -
BN Kumarguru,
M. Natarajan,
Dayananda S Biligi,
A R Raghupathi
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/15035.6786
Subject(s) - giant cell , pathology , langhans giant cell , stain , foreign body giant cell , haematoxylin , autopsy , staining , histiocyte , mitotic index , lung , medicine , biology , mitosis , microbiology and biotechnology
Macrophages undergo fusion to form multinucleated giant cells (MGC) in several pathologic conditions. The exact mechanism of their generation is still unclear. MGC are a common feature of granulomas that develop during various inflammatory reactions.