Open AccessClaudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
Author(s) -
Masoud Hatefi,
Nabi Ramezani Pirabadi,
Javaher Khajavikhan,
Molouk Jaafarpour
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14833.6596
Subject(s) - medicine , buttocks , fasciotomy , methylprednisolone , surgery , anesthesia , adverse effect
Nicolau syndrome is a rare drug reaction due to intramuscular injection administration that can lead to limb loss or even death. A 3.8-year-old Iranian boy received an intramuscular injection of Benzathine Penicillin. Immediately after injection the child developed lower limb pain and livedoid discolouration and was referred to our department. The patient was diagnosed to develop Nicolau syndrome and fasciotomy carried out due to compartment syndrome. Pharmacologic therapy with Heparin, Cefazolin and Methylprednisolone was initiated. On 18(th) day, he was discharged, although he was not able to move. Finally, after 6 months of care at home, physiotherapy and Electromyography (EMG) at regular intervals, the child was gradually able to move and his claudication improved.