Open AccessFibrinogen Degradation Products and Periodontitis: Deciphering the Connection
Author(s) -
Shweta Dikshit
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14729.6922
Subject(s) - periodontitis , fibrinogen , medicine , d dimer , fibrin , chronic periodontitis , fibrinolysis , gastroenterology , immunology
Fibrinogen degradation products (e.g. D-dimer) arise from digested fibrin clots and fibrinogen. Elevated concentrations accompany activation of coagulation and fibrinolysis and indicate chronic inflammatory diseases. D-Dimer tests are a quick, noninvasive method to rule out abnormal clotting. Periodontitis strongly affects the haemostatic system and evokes a procoagulant state. Correlation of chronic periodontitis with early indicators of disease (biomarkers) might be useful.