Open AccessChromosomal Abnormalities in Infertile Men from Southern India
Author(s) -
Jaganathan Suganya,
Smita B. Kujur,
Kamala Selvaraj,
Muthiah S. Suruli,
Geetha Haripriya,
Chandra R Samuel
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14429.6247
Subject(s) - infertility , male infertility , karyotype , gynecology , endocrine system , population , biology , medicine , genetics , gene , chromosome , pregnancy , hormone , environmental health
Male infertility has been associated with aneuploidies and structural chromosomal abnormalities, Yq microdeletions and specific gene mutations and/or polymorphisms. Besides genetic factors, any block in sperm delivery, endocrine disorders, testicular tumours, infectious diseases, medications, lifestyle factors and environmental toxins can also play a causative role. This study aimed to determine the constitutional karyotype in infertile males having normal female partners in a south Indian population.