Open AccessInvitro Anti-mycotic Activity of Hydro Alcoholic Extracts of Some Indian Medicinal Plants against Fluconazole Resistant Candida albicans
Author(s) -
Saranya Varadarajan,
Malathi Narasimhan,
Malaiyandi Malaisamy,
D. Chamundeeswari
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14178.6273
Subject(s) - carica , trigonella , fluconazole , traditional medicine , candida albicans , bark (sound) , phytochemical , cinnamomum , biology , agar diffusion test , microbiology and biotechnology , medicine , antifungal , horticulture , antibacterial activity , bacteria , cassia , ecology , genetics , alternative medicine , traditional chinese medicine , pathology
Candidiasis is one of the most common opportunistic infections caused by Candida albicans. Fluconazole is the drug of choice for prevention and management of this condition. However, the emergence of fluconazole resistant candidal strains has become a major concern. Many herbs like fenugreek, cinnamon, papaya, oregano, garlic are rich in phytochemical constituents known to express antimycotic activity. With the available information, the present research study was carried out to assess the invitro anti-mycotic activity of hydro alcoholic extracts of Trigonella foenum-graecum seeds, Cinnamomum verum bark and Carica papaya leaves and seeds against fluconazole resistant Candida albicans.