
Radiobiological Response of Cervical Cancer Cell Line in Low Dose Region: Evidence of Low Dose Hypersensitivity (HRS) and Induced Radioresistance (IRR)
Author(s) -
Saikat Das,
Rabiraja Singh,
Daicy George,
T.S. Vijaykumar,
Subhashini John
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14120.6074
Subject(s) - radioresistance , hela , clonogenic assay , cervical cancer , nuclear medicine , cell culture , radiobiology , medicine , relative biological effectiveness , cancer research , radiation therapy , oncology , radiation , cancer , biology , physics , optics , genetics
Purpose of the present study was to examine the response of cervical cancer cell line (HeLa cell line) to low dose radiation using clonogenic assay and mathematical modeling of the low dose response by Joiner's induced repair model.