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Nine-Months Clinical Outcome of Biodegradable Polymer Coated Sirolimus-eluting Stent System: A Multi-Centre “Real-World” Experience
Author(s) -
R.N. Sarma,
Jayesh Prajapati,
Asif Raheem,
Kamlesh Thakkar,
Shivani Kothari,
Ashok Thakkar
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/14060.6403
Subject(s) - medicine , mace , sirolimus , stent , target lesion , myocardial infarction , surgery , adverse effect , revascularization , cardiology , conventional pci , percutaneous coronary intervention
The main culprit in first-generation drug eluting stents is 'durable' polymer, whose continuous presence may impair arterial healing and ultimately have a negative impact on late outcomes. The main enigma behind the biodegradable polymer usage is its degradation after elution of drug. This reduces adverse events in unselected patients with complex coronary artery lesions treated with biodegradable polymer coated sirolimus-eluting stents.

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