Open AccessA Study on Longevity of Immune Response after Vaccination with Salmonella Typhi Vi Conjugate Vaccine (Pedatyph™) in Children
Author(s) -
Balaji Chinnasami,
Kanimozhi Sadasivam,
Vivekanandhan Aravindhan,
Prema Arunachalam,
Sekar Pasupathy
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/13302.5903
Subject(s) - vaccination , medicine , typhoid fever , conjugate vaccine , salmonella typhi , booster dose , titer , regimen , immune system , immunization , immunology , typhoid vaccine , antibody , booster (rocketry) , antibody titer , virology , biology , biochemistry , escherichia coli , gene , physics , astronomy
Owing to the limitations of the conventional polysaccharide vaccines, global efforts have been made to develop conjugated polysaccharide vaccines for typhoid. Duration of immune response induced by these vaccines is critical to define the efficacy and frequency of required booster dose. This study was done to determine the duration of immune response following vaccination with Salmonella Typhi Vi conjugate vaccine (Pedatyph™) in children and to assess the booster effect of second dose of conjugate typhoid vaccine.