Open AccessSmall Bowel Carcinoids: A Single Surgeon’s Experience in Southern India
Author(s) -
Sreevathsa M Ramachar,
Nishchit Hegde
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/13144.6737
Subject(s) - medicine , abdomen , chromogranin a , anastomosis , histopathology , gastroenterology , bowel obstruction , carcinoid tumour , mesentery , colonoscopy , surgery , immunohistochemistry , pathology , colorectal cancer , cancer
Small bowel carcinoid tumours are indolent neuroendocrine tumours usually seen in the 6(th) and 7(th) decades. Most often, they are silent with non-specific symptoms. They generate serotonin, provoking a desmoplastic reaction in the mesentery leading to bowel ischemia and obstruction. While CECT abdomen can help raise suspicion and show regional spread, elevated 24-hour urinary 5-HIAA levels, histopathology and immunohistochemistry for Chromogranin A are confirmatory.