Open AccessAn Atypical Case of POEMS Syndrome with an Osteolytic Bone Lesion
Author(s) -
Rahul Kumar,
Nayha Handa,
S. H. Chandrashekhara,
Usha Thingujam,
Anuradha Singh
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12998.6099
Subject(s) - poems syndrome , plasma cell dyscrasia , organomegaly , polyneuropathy , dyscrasia , medicine , lesion , pathology , sternum , plasma cell , bone marrow , surgery , immunoglobulin light chain , antibody , immunology
POEMS syndrome is a rare multisystem disorder with an underlying plasma cell dyscrasia associated with Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes. Usually it is associated with sclerotic bone lesions. It usually manifests in 5(th)-6(th) decade of life with a mean survival period of eight years. We report an unusual case of a 28-year-old male diagnosed with POEMS syndrome and had a lytic bone lesion the in sternum.