Open AccessC D 34 and Mast Cell Analysis in Normal Oral Mucosa and Different Grades of Oral Squamous Cell Carcinoma: A Comparative Study
Author(s) -
Pargatsingh Kathuriya,
Anirudha Bartake,
Sangeeta Palaskar,
Bindiya Narang,
Sachin Patil,
Rasika Pawar
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12656.6223
Subject(s) - angiogenesis , cd34 , mast cell , medicine , basal cell , metastasis , pathology , cell , cancer , cancer research , biology , immunology , stem cell , genetics
Oral Squamous Cell Carcinoma (OSCC) remains a serious health problem worldwide. Prognosis of OSCC is poor and long term survival rate still remains below 50%. Angiogenesis or neovascularisation plays an important role in tumour progression and metastasis. Mast cells have been implicated in promoting tumour angiogenesis, especially of digestive tract, little is known in OSCC.