Open AccessLangerhans Cell Expression in Oral Submucous Fibrosis: An Immunohistochemical Analysis
Author(s) -
Bharghavi Narayanan
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12608.6196
Subject(s) - oral submucous fibrosis , pathology , immunohistochemistry , langerhans cell , haematoxylin , medicine , epithelium , population , fibrosis , antigen , biology , immunology , environmental health
Langerhans cells (LCs), are dendritic cells of the epithelium which play a role in an array of oral lesions from gingivitis to oral cancer. Oral Submucous Fibrosis (OSMF), a potentially malignant disorder (PMD), is an insidious chronic disease with juxta-epithelial inflammatory changes leading to fibrosis. Langerhans cells (LCs) may play a part in the ongoing inflammatory dysregulation of OSMF.