Open AccessNafcillin Implicated in A Case of Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis
Author(s) -
Changqing Xie,
Suchita S Pancholi,
Niti Armistead
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12573.5839
Subject(s) - medicine , nafcillin , dermatology , rash , prednisone , leukocytoclastic vasculitis , vasculitis , differential diagnosis , skin biopsy , biopsy , gastroenterology , pathology , antibiotics , disease , microbiology and biotechnology , biology , penicillin
Leukocytoclastic vasculitis (LV) is a rare hypersensitive reaction involving the small vessels, which is usually mediated by drugs. Very few cases of nafcillin -associated LV have been reported. Here, we reported a case of LV with the presentation of skin rashes and gastrointestinal bleeding after receiving nafcillin, evidenced by endoscopy and skin biopsy. The symptoms resolved after withdrawal of nafcillin and the addition of prednisone treatment. LV should be considered in the differential diagnosis of erythematous rash, especially with gastrointestinal symptoms after the exposure.