Open AccessIsolated Langerhans Histiocytosis in Thyroid: Thyroidectomy or Chemotherapy?
Author(s) -
Anoop Attakkil,
Vandana Thorawade,
Mohan Jagade,
Rajesh Kar,
Kartik Parelkar
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12313.6466
Subject(s) - langerhans cell histiocytosis , thyroid , medicine , histiocytosis , thyroidectomy , chemotherapy , pathology , presentation (obstetrics) , disease , radiology
Langerhans cell histiocytosis (LCH) is a rare disorder of mononuclear phagocytic system whose clinical presentation varies from the localised involvement of a single bone to a widely disseminated disease. Langerhans cell histiocytosis rarely involves the thyroid gland and isolated involvement of thyroid is even rarer. We report a case of an eight-year-old male child diagnosed with Langerhans cell histiocytosis limited to thyroid gland with review of literature. Should thyroidectomy be done or proceed with chemotherapy? Our case report raises this question with a note on the role of 18 fluoro deoxy glucose positron emission tomography-computed tomography in the management of the same.