Open AccessIn Vitro Fractional Inhibitory Concentration (FIC) Study of Cefixime and Azithromycin Fixed Dose Combination (FDC) Against Respiratory Clinical Isolates
Author(s) -
Saiprasad Patil,
Anoop L. Hajare,
Manjusha Patankar,
Krupa Krishnaprasad
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12092.5560
Subject(s) - cefixime , azithromycin , minimum inhibitory concentration , medicine , antibiotics , microbiology and biotechnology , respiratory tract infections , veterinary medicine , biology , respiratory system , cephalosporin
Acute respiratory infections (ARI) contribute to more than 75% of health care seeking in primary health care facilities in India. Respiratory tract infections (RTIs) are managed frequently by β-lactam, macrolide and fluroquinolone class of antibiotics. However, these recommended classes of antibiotic have shown resistance in community settings. Antibiotic combinations may provide broader spectrum not only in terms of coverage but also to overcome multiple resistance mechanisms overcoming individual class limitations.