Open AccessXIAP and Ki-67: A Correlation Between Antiapoptotic and Proliferative Marker Expression in Benign and Malignant Tumours of Salivary Gland: An Immunohistochemical Study
Author(s) -
Bhupesh Bagulkar,
Madhuri Gawande,
Minal Chaudhary,
Amol Gadbail,
Swati Patil,
Smita Bagulkar
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/11690.5604
Subject(s) - xiap , immunohistochemistry , malignancy , ki 67 , pathology , inhibitor of apoptosis , apoptosis , medicine , cancer research , biology , programmed cell death , caspase , biochemistry
Impaired balance between cell proliferation and apoptosis is crucial to the development of malignant neoplasm. The purpose of this study was to evaluate and compare the expression of X-Linked inhibitor of apoptotic protein (XIAP) (antiapoptotic marker) and Ki-67 (proliferative marker) expression in benign and malignant salivary gland (SG) tumours.