Open AccessThe Importance of Cytokeratin 19 Expression in the Differentiation of Basal Cell Carcinoma and Trichoepithelioma
Author(s) -
Recep Bedir,
İbrahim Şehitoğlu,
Cüneyt Yurdakul,
İsmail Sayğın,
Pelin Üstüner,
Nursel Dılek
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/10915.5414
Subject(s) - trichoepithelioma , cytokeratin , pathology , staining , basal cell carcinoma , immunohistochemistry , basal (medicine) , biopsy , biology , carcinoma , outer root sheath , human skin , basal cell , medicine , endocrinology , genetics , insulin
Basal cell carcinoma (BCC) is the most common skin neoplasm reported in human. On the other hand, trichoepithelioma (TE) is a rare, benign tumour of skin adnexa. The differentiation of BCC and TE may be difficult since their morphological findings are similar. In a few studies, it has been determined that undifferentiated basaloid cells are highly positively stained with cytokeratin 19.