Open AccessComparative Evaluation of Disc Diffusion and E-test with Broth Micro-dilution in Susceptibility testing of Amphotericin B, Voriconazole and Caspofungin against Clinical Aspergillus isolates
Author(s) -
Prashant Gupta,
Vineeta Khare,
Deepak Kumar,
Abrar Ahmad,
Gopa Banerjee,
Mastan Singh
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/10467.5395
Subject(s) - voriconazole , caspofungin , amphotericin b , microbiology and biotechnology , aspergillus fumigatus , agar dilution , aspergillus , agar diffusion test , aspergillosis , agar dilution method , aspergillus terreus , antifungal , aspergillus flavus , medicine , chemistry , biology , minimum inhibitory concentration , immunology , antibiotics , antibacterial activity , bacteria , genetics
Clinical importance of Aspergillus has increased over the past few decades because of rise in immunosuppressive drugs and immune-modulating diseases. Antifungal susceptibility of Aspergillus is rarely performed by clinical laboratories because of lack of easier method. This study has investigated and compared susceptibility pattern of Aspergillus isolates by disc diffusion, E-test and broth micro-dilution for amphotericin B, voriconazole and caspofungin.