Open AccessAntimicrobial Activity and Stability of Electron Beam Irradiated Dental Irrigants
Author(s) -
Shetty Av,
A Geethashri,
Palaksha Kj,
Kandikere R. Sridhar,
Ganesh Sanjeev
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/9449.5180
Subject(s) - antimicrobial , sodium hypochlorite , enterococcus faecalis , chlorhexidine , streptococcus mutans , candida albicans , staphylococcus aureus , chemistry , microbiology and biotechnology , irradiation , dentistry , bacteria , medicine , biology , genetics , physics , organic chemistry , nuclear physics
The electron beam (e-beam) radiation is considered as an effective means of sterilization of healthcare products as well as to induce the structural changes in the pharmaceutical agents/drug molecules. In addition to structural changes of pharmaceutical it also induces the formation of low molecular weight compounds with altered microbiological, physicochemical and toxicological properties. Among the several known medicaments, sodium hypochlorite (NaOCl) and chlorhexidine digluconate (CHX) are used as irrigants in dentistry to kill the pathogenic microorganisms like Enterococcus faecalis, Staphylococcus aureus, Streptococcus mutans and Candida albicans inhabiting the oral cavity.