Open AccessPrimary Renal Large Cell Neuroendocrine Carcinoma in a Young Man
Author(s) -
Cornerstone Wann,
Nirmal Thampi John,
Rajesh Kumar
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/9443.5179
Subject(s) - histopathological examination , medicine , nephrectomy , pathology , immunohistochemistry , kidney , gastrointestinal tract , renal cell carcinoma , neuroendocrine carcinoma , calcification
Neuroendocrine tumours are usually located in the gastrointestinal or respiratory tract. A 23-year-old man was evaluated for loss of weight and a palpable left loin mass. CECT showed a large heterogeneously enhancing mass with calcification arising from the left kidney. He underwent an open radical nephrectomy. Histopathological examination revealed a large cell neuroendocrine carcinoma (LCNEC). LCNEC of the kidney is extremely rare and portends poor prognosis. It is usually a histopathological surprise and requires immunohistochemistry for confirmation.