Open AccessRole and Efficacy of L-PRFmatrix in the Regeneration of Periodontal Defect: a New Perspective
Author(s) -
Pravin Patil,
Rajesh Kumar,
Krishna Kripal
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/9240.5245
Subject(s) - platelet rich fibrin , fibrin , regeneration (biology) , wound healing , biomedical engineering , hard tissue , dentistry , medicine , surgery , microbiology and biotechnology , biology , immunology
The ultimate goal of periodontal therapy is to achieve complete wound healing and regeneration of the periodontal unit. The therapeutic use of L-PRF matrix constitutes a relatively new biotechnology that has been a breakthrough in the acceleration of hard and soft tissue healing. Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified processing and without biochemical blood handling. The slow polymerization during PRF preparation seems to generate a fibrin network very similar to the natural one. Such a network leads to a more efficient cell migration and proliferation and thus cicatrization. This article proposes an overview of use of platelet-rich fibrin in management of periodontal hard and soft tissue defects and goes on to describe the clinical benefits of PRF and its advantage over PRP.