Open AccessCommon Matrix Metalloproteinases ( M MP - 8, -9, -25, and -26) Cannot Explain Dentigerous Cyst Expansion
Author(s) -
Juho Suojanen,
Niko Lehtonen,
Esa Färkkilä,
Jarkko Hietanen,
Olli Teronen,
Timo Sorsa,
Jaana Hagström
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/9221.4899
Subject(s) - dental follicle , dentigerous cyst , matrix metalloproteinase , pathology , cyst , matrix (chemical analysis) , follicle , immunohistochemistry , epithelium , medicine , biology , anatomy , chemistry , mesenchymal stem cell , chromatography
Mechanisms of the dentigerous cyst formation from the normal eruption follicle is unknown but disturbances in the proteolytic activity have been suspected, since the growth of these cysts is accompanied by local bone destruction. The aim of the present study was to evaluate the expression of matrix metalloproteinases (MMP) in human dental dentigerous cysts and healthy dental follicles.