Open AccessInfluence of Insulin-Like Growth Factor-I on Maturation and Fertilization Rate of Immature Oocyte and Embryo Development in NMRI Mouse with TCM199 and α -MEM Medium
Author(s) -
Mehdi Akbartabar Toori,
Esmaeil Mosavi,
Mohsen Nikseresht,
Mehrzad Jafari Barmak,
Reza Mahmoudi
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/9129.5242
Subject(s) - blastocyst , oocyte , human fertilization , in vitro maturation , andrology , embryo , biology , embryogenesis , in vitro fertilisation , insulin like growth factor , chemistry , growth factor , microbiology and biotechnology , anatomy , medicine , genetics , receptor
In vitro maturation (IVM) of oocytes and subsequent, in vitro fertilization (IVF) for the generation of embryos in the laboratory has important values. Growth factors are a component of a complex system of autocrine and paracrine factors that have a regulatory role in ovarian function and affect oocyte maturation. Therefore, the aim of this study is to evaluate the effect of IGF-I on IVM and IVF of mice oocytes during culture with α-MEM and TCM199 medium.