Open AccessEffect of Vitamin C on Male Fertility in Rats Subjected to Forced Swimming Stress
Author(s) -
Sanghishetti Vijayprasad,
Balasaheb B. Ghongane,
Nayak Bb
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/8432.4622
Subject(s) - oxidative stress , sperm , antioxidant , vitamin c , ascorbic acid , vitamin , medicine , sperm motility , endocrinology , infertility , context (archaeology) , vitamin e , motility , physiology , biology , andrology , biochemistry , pregnancy , food science , paleontology , genetics
Stress is defined as a general body response to initially threatening external or internal demands, involving the mobilization of physiological and psychological resources to deal with them. Recently, oxidative stress has become the focus of interest as a potential cause of male infertility. Normally, equilibrium exists between reactive oxygen species (ROS) production and antioxidant scavenging activities in the male reproductive organs. The ascorbic acid is a known antioxidant present in the testis with the precise role of protecting the latter from the oxidative damage. It also contributes to the support of spermatogensis at least in part through its capacity to maintain antioxidant in an active state.