Open AccessChemoresistant Gestational Trophoblastic Neoplasia: A Case Report
Author(s) -
Cp S
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/8274.4645
Subject(s) - medicine , gestational trophoblastic disease , gestational trophoblastic neoplasia , placental site trophoblastic tumor , hysterectomy , chemotherapy , gestation , biopsy , disease , trophoblastic neoplasm , trophoblastic tumor , gynecology , obstetrics , cancer , uterus , pregnancy , fetus , placenta , surgery , biology , genetics
Gestational trophoblastic neoplasia (GTN) is a disease of women in reproductive age. It is one of the most chemotherapy responsive and highly curable cancer. It is diagnosed when there is clinical, radiologic, pathologic, and/or hormonal evidence of persistent or relapsed gestational trophoblastic disease. In most instances, it is cured by surgical evacuation of the uterus. If persistent, it is treated with chemotherapy which provides response in >90% of the cases. In the unresponsive persistent cases and if the women has completed her child bearing, hysterectomy is generally recommended. Here, we report a rare case of chemoresistant GTN which was confirmed to be placental-site trophoblastic tumour (PSTT) on biopsy.