Open AccessComparision of three Laboratory Tests for Detection of Ampc ß Lactamases in Klebsiella Species and E. Coli
Author(s) -
Deepashri Maraskolhe,
Vijayshri Deotale,
DK Mendiratta,
P Narang
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/8256.4432
Subject(s) - cefoxitin , cloxacillin , microbiology and biotechnology , klebsiella , cefotetan , biology , klebsiella pneumoniae , antibiotics , bacteria , antibiotic resistance , escherichia coli , imipenem , penicillin , staphylococcus aureus , biochemistry , gene , genetics
AmpC β lactamases are one of the important causes of drug resistance in gram negative bacteria. Failure to detect these enzymes in the laboratory has contributed to therapeutic failures but there are till date no standard guideline available. This study was therefore undertaken to evaluate three phenotypic laboratory tests and the inhibitors used in two of the tests to detect AmpC β lactamases produced by E. coli and Klebsiella species as they are most commonly isolated organisms.