Open AccessThe Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study
Author(s) -
Sumit Roy Tapadar,
Maumita Das,
Arunabha Datta Chaudhuri,
Sneha Basak,
Anil Baran Singha Mahapatra
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/8176.4869
Subject(s) - medicine , theophylline , copd , lama , bronchodilator , tolerability , inhaler , adverse effect , spirometry , sputum , anesthesia , asthma , tuberculosis , pathology
Over the past several decades, the use of drug therapy in COPD has expanded, and provides an optimistic picture. Methyixanthines are used freely in COPD. Of them, Theophylline is an age old bronchodilator and anti-inflammatory agent while Acebrophylline is a newer one. Both are used as add on therapy in management of stable COPD patients on LAMA (long acting muscarinic antagonists like Tiotropium) in present day respiratory practice. This study was designed to compare the efficacy as well as tolerability/side-effects of these two drugs at recommended doses.