Open AccessFunctioning Oxyphil Parathyroid Adenoma: A Case Report
Author(s) -
Rajendra B Metgudmath,
Vinita V. Metgudmath,
Prakash R Malur,
Amal T. Das,
Anjali R. Metgudmath
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/7724.4297
Subject(s) - primary hyperparathyroidism , medicine , parathyroid adenoma , parathyroidectomy , histopathology , parathyroid hormone , differential diagnosis , adenoma , parathyroid carcinoma , parathyroid neoplasm , hyperparathyroidism , pathology , calcium
Oxyphil parathyroid adenomas are rare and clinical features of patients with this entity are not well defined. We are presenting a case of primary hyperparathyroidism with marked elevation of parathyroid hormone (PTH) and near normal calcium levels, that underwent parathyroidectomy. Histopathology revealed an oxyphil adenoma which showed positivity for PTH on immunohistochemical staining. Post - operatively, there was a significant decline in both PTH and alkaline phosphatase levels. Benign oxyphil adenomas may mimic parathyroid carcinomas, both in terms of clinical features and tumour size; and they should be considered in the differential diagnosis of patients with primary hyperparathyroidism.