Open AccessImmunohistochemical Analysis of P53 and PRB in Esophageal Squamous Cell Carcinoma
Author(s) -
Biswajit Dey,
Vandana Raphael,
Yookarin Khonglah,
Kyrshanlang G Lynrah
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/7428.4309
Subject(s) - immunostaining , immunohistochemistry , pathology , carcinogenesis , medicine , metastasis , carcinoma , lymph node , stage (stratigraphy) , cancer research , biology , cancer , paleontology
Esophageal squamous cell carcinoma (ESCC) is one of the fatal cancers with a high incidence rate in Asia. Many genes including p53 and pRb play an important role in its carcinogenesis. Expressions of p53 and pRb proteins have been associated with prognosis of ESCC.