Open AccessEmbryonal/Fetal Subtype Hepatoblastoma: A Case Report
Author(s) -
Ioannis Spyridakis,
Chrysostomos Kepertis,
Lampropoulos,
Mouravas,
Antonios Filippopoulos
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/6643.4823
Subject(s) - hepatoblastoma , pathology , medicine , embryonal rhabdomyosarcoma , fetus , liver tumor , alpha fetoprotein , abdominal mass , histogenesis , germ cell tumors , yolk sac , biology , rhabdomyosarcoma , immunohistochemistry , pregnancy , sarcoma , chemotherapy , hepatocellular carcinoma , embryo , genetics , microbiology and biotechnology
Hepatoblastoma is the most common primary liver tumor of childhood and after neuroblastoma and nephroblastoma the third most common abdominal neoplasm in this age group. Hepatoblastoma is an embryonal tumor classified by histology as epithelial (including pure fetal subtype, mixed embryonal/fetal subtype, macrotrabecular subtype and small cell undifferentiated subtype), mixed epithelial and mesenchymal type (with teratoid and non-teratoid features) and hepatoblastoma not otherwise specified. We present a case of a five-months old girl with embryonal/fetal subtype hepatoblastoma. The clinical presentation was asymptomatic abdominal mass. Ultrasound and MRI scan demonstrated a solid hepatic tumor. She presented thrombocytosis and serum alpha-fetoprotein was increased. A left lobe hepatectomy was performed and the pathological examination revealed complete excision of a mixed embryonalfetal subtype hepatoblastoma.