Open AccessDrug Induced Erythema Multiforme: Two Case Series with Review of Literature
Author(s) -
Shreyas N Shah,
Girish Chauhan,
Bhari Sharanesha Manjunatha,
Kapil Dagrus
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/10173.4761
Subject(s) - erythema multiforme , dermatology , medicine , mycoplasma pneumoniae , mucocutaneous zone , drug , pathology , disease , pharmacology , pneumonia
Erythema Multiforme, (EM) an uncommon, acute inflammatory reactive mucocutaneous disorder and primary allergies confined to the oral mucosa. However the subsequent attacks can produce more severe forms of EM involving the skin. Manifestations of EM are varied and present a diagnostic dilemma because infections (particularly herpes simplex and mycoplasma pneumoniae) and drugs seem to predispose towards development of EM. We report two cases of EM in which drugs (Dioclofenac sodium & Amoxycilline) seems to be precipitating factor. In addition, the article reviews various aspects of EM as relevant to dental practice and highlight the associated potential etiologic agents, pathogenic mechanisms and therapies.