Open AccessIncreased Levels of Markers of Oxidative Stress and Inflammation in Patients with Rheumatic Mitral Stenosis Predispose to Left Atrial Thrombus Formation
Author(s) -
Vinay Kumar Pulimamidi,
Vengatesan Murugesan,
Medha Rajappa,
Santhosh Satheesh,
Kottenyen Thazhath Harichandrakumar
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/7251.3570
Subject(s) - medicine , thrombus , malondialdehyde , oxidative stress , cardiology , c reactive protein , inflammation , platelet activation , stenosis , sialic acid , gastroenterology , platelet , biochemistry , chemistry
Rheumatic mitral stenosis (MS) causes stagnation of blood flow, leading to thrombus formation in the left atrium (LA), which may lead to systemic thromboembolic complications. We compared alterations in circulating levels of pro-/anti-oxidants and markers of inflammation in patients of severe rheumatic MS with and without LA thrombus and studied their predictive power to detect the presence of LA thrombus in patients with rheumatic MS.