Open AccessVigabatrin induced Cell loss in the Cerebellar Cortex of Albino Rats
Author(s) -
Deepa Singh
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/6187.3610
Subject(s) - vigabatrin , cerebellum , ataxia , cerebellar cortex , cerebellar ataxia , medicine , epilepsy , cortex (anatomy) , purkinje cell , anesthesia , neuroscience , anticonvulsant , psychology , psychiatry
Vigabatrin is used as the drug of choice in resistant epilepsy and infantile spasms. Ataxia, tremors and abnormal gait have been frequently reported following the use of this drug, indicating an involvement of the cerebellum.