Open AccessCraniofacial Duplication: A Case Report
Author(s) -
Pradeep Suryawanshi,
Mayuresh M. Deshpande,
Nitisha Verma,
Mahendrakar,
S Mahendrakar
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/5658.3395
Subject(s) - gene duplication , craniofacial , conjoined twins , gastrointestinal system , craniofacial abnormality , medicine , anatomy , biology , genetics , gene
A craniofacial duplication or diprosopus is an unusual variant of conjoined twinning. The reported incidence is one in 180,000-15 million births and 35 cases have been reported till date. The phenotype is wide, with the partial duplication of a few facial structures to complete dicephalus. A complete duplication is associated with a high incidence of anomalies in the central nervous system, cardiovascular system, gastrointestinal system and the respiratory system, whereas no major anomalies are found in the infants with a partial duplication. A term baby with the features of a craniofacial duplication has been described, with the proposed theories on embryogenesis and a brief review of the literature.