Open AccessGiant Sporadic Low Grade Malignant Peripheral Nerve Sheath (MPNST) of Left Thigh
Author(s) -
Dhiraj B. Nikumbh,
Kishor H Suryawanshi,
Nandkumar V Dravid,
Tushar Patil,
C.M. Rokade
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/5511.3082
Subject(s) - medicine , malignant peripheral nerve sheath tumor , thigh , trunk , neural crest , peripheral , sarcoma , incidence (geometry) , pathology , population , head and neck , nerve sheath neoplasm , anatomy , neurofibromatosis , surgery , biology , embryo , ecology , physics , environmental health , optics , microbiology and biotechnology
Malignant Peripheral Nerve Sheath Tumours (MPNST) are rare spindle- cell sarcomas which are derived from the schwann cells or the pleuripotent cells of the neural crest. MPNSTs are usually located in the peripheral nerve trunk roots, extremities and in the head and neck region. These tumours may arise as sporadic variants or in patients with neurofibromatosis1 (NF1). The estimated incidence of MPNSTs in the patients with NF1is 2-5% as compared to a 0.001% incidence in the general population. Herein, we are reporting a case of a giant sporadic (NF1 independent) low grade MPNST of the left thigh in 65 year female patient, which had a good prognosis.