Open AccessA Case of Ankylosing Spondylitis and Discussion of the Literature
Author(s) -
M.P. Ranjith
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/5219.3050
Subject(s) - ankylosing spondylitis , infliximab , medicine , nonsteroidal , spondylitis , pathogenesis , disease , immunology , intensive care medicine , tumor necrosis factor alpha
Ankylosing spondylitis (AS) is a systemic inflammatory disease. Its pathogenesis has not been completely understood, but the HLA-B 27 positive immune cells are thought to be involved. Nonsteroidal anti-inflammatory agents are the first line drugs and they effectively relieve the symptoms. Biological agents such as Infliximab may help in targeting the underlying inflammatory process and have been used recently. Here, we are reporting a case of AS with established classical skeletal deformities.