Open AccessThe Role of Immunohistochemistry in the Analysis of the Spectrum of Small Round Cell Tumours at a Tertiary Care Centre
Author(s) -
Lawrence D’Cruze,
Ruma Dutta,
Shalinee Rao,
Anuradha Ray,
Suresh Varadarajan,
Sarah Kuruvilla
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/5127.3132
Subject(s) - cd99 , chromogranin a , pathology , immunohistochemistry , cytokeratin , lymph node , immunophenotyping , medicine , synaptophysin , biology , antigen , vimentin , immunology
The term, "Small Round - Cell Tumours" (SRCT) describes a group of highly aggressive malignant neoplasms which are composed predominantly of small and monotonous undifferentiated cells with high nucleocytoplasmic ratios. Immunohistochemistry (IHC) plays a crucial role in catagorizing the small round - cell tumours.