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An Unusual Type of Kidney Stone
Author(s) -
Anne-Sophie De Koninck,
LuitzenAlbert Groen,
Heleen Maes,
Alain Verstraete,
Veronique Stove,
J. Delanghe
Publication year - 2016
Publication title -
clinical laboratory
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.361
H-Index - 46
ISSN - 1433-6510
DOI - 10.7754/clin.lab.2015.150605
Subject(s) - sulfasalazine , psoriatic arthritis , medicine , metabolite , renal function , kidney stones , urology , arthritis , ulcerative colitis , disease
A very rare case of acetylsulfapyridine nephrolithiasis is presented in a 54-year-old female patient who had been prescribed sulfasalazine (6 x 500 mg/day) because of psoriatic arthritis for the last 9 years. The patient's renal function was only slightly impaired. Reflectance infrared spectroscopy and gas chromatography-mass spectrometry allowed the identification of the chemical nature of the stone. As acetylsulfapyridine is a metabolite of sulfasalazine, administration of the latter drug was the cause of the nephrolithiasis.

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