English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Myostatin (MSTN) is a negative regulator of muscle growth, which restrains the proliferation and differentiation of myoblasts. To understand the role of two  mstn  genes of  Takifugu bimaculatus , the full-length cDNAs of 1131 bp  Tbmstn1  and 1,080 bp  Tbmstn2  were obtained from the  T. bimaculatus ’ genomic database, which encodes 376 and 359 amino acids, respectively. The results of qRT-PCR showed that  Tbmstn1  was expressed in the eye, kidney, spleen, skeletal muscle, gill, and brain, and the expression level in the skeletal muscle was extremely significantly higher than in other examined tissues.  Tbmstn2  was expressed in the skin, skeletal muscle, gill, and brain, and had the highest expression in the skeletal muscle, followed by expression in the brain. Meanwhile, in different stages of embryonic development, the expression of  Tbmstn1  started from the gastrula stage. Its expression in the eye-pigment formation stage and hatching stage was significantly higher than that in other stages. The  Tbmstn2  was expressed in all examined embryonic stages with different levels, and the highest expression was detected in the eye-pigment formation stage. These results suggested that  Tbmstn1  and  Tbmstn2  may involve in the development of skeletal muscle, and  Tbmstn2  may be related to the formation of nervous system.

Characterization of two myostatin genes in pufferfishTakifugu bimaculatus: sequence, genomic structure, and expression