Open AccessBRCA1 overexpression attenuates breast cancer cell growth and migration by regulating the pyruvate kinase M2-mediated Warburg effect via the PI3K/AKT signaling pathway
Author(s) -
Xiuli Liu,
Hanxu Liu,
Lingyu Zeng,
Yuetao Lv
Publication year - 2022
Publication title -
peerj
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.927
H-Index - 70
ISSN - 2167-8359
DOI - 10.7717/peerj.14052
Subject(s) - pi3k/akt/mtor pathway , warburg effect , protein kinase b , cancer research , microbiology and biotechnology , pyruvate kinase , cell growth , signal transduction , chemistry , biology , cancer , cancer cell , glycolysis , metabolism , biochemistry , genetics