Open AccessLeucemia/linfoma T del adulto en pacientes infectados con HTLV-1: reporte de dos casos de Colombia
Author(s) -
Edwin Abraham Medina Medina,
Rocío Ordúz,
Olga Lucía Morales-Reyes,
Óscar Núñez Martínez,
Margarita Baldión,
Mario Arturo Isaza
Publication year - 2013
Publication title -
biomédica/biomedica
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.26
H-Index - 28
eISSN - 2590-7379
pISSN - 0120-4157
DOI - 10.7705/biomedica.v33i4.1429
Subject(s) - lymphoma , medicine , leukemia , immunohistochemistry , histology , western blot , virus , t cell leukemia , flow cytometry , virology , pathology , immunology , biology , gene , biochemistry
Adult T-cell leukemia/lymphoma (ATLL) is a malignant neoplasia of mature CD4+ T lymphocytes,resulting from infection with human T-lymphotropic virus type 1 (HTLV-1), with several systemic and cutaneous manifestations. We present two cases of adult T-cell leukemia/lymphoma, in patients from the Colombian Southwestern region, whose diagnoses were confirmed by histology, immunohistochemistry, flow cytometry, ELISA and Western blot tests. We also discuss about the virus and how to make this diagnosis in countries like Colombia.