Open AccessBacteremia after Bacillus clausii administration for the treatment of acute diarrhea: A case report
Author(s) -
Juan Pablo García,
Julián Andrés Hoyos-Pulgarín,
John Alexander Alzate,
Edilberto Cristancho
Publication year - 2021
Publication title -
biomédica/biomedica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.26
H-Index - 28
eISSN - 2590-7379
pISSN - 0120-4157
DOI - 10.7705/biomedica.5662
Subject(s) - medicine , diarrhea , enterocolitis , bacteremia , gastroenterology , probiotic , dermatology , surgery , antibiotics , microbiology and biotechnology , biology , bacteria , genetics
Bacillus clausii is a gram-positive rod used as a probiotic to treat diarrhea and the side effects of antibiotics such as pseudomembranous colitis. We report a case of B. clausii bacteremia in a non-immunocompromised patient with active peptic ulcer disease and acute diarrhea. The probiotic was administered during the patient´s hospitalization due to diarrhea of infectious origin. B. clausii was identified in the bloodstream of the patient through Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) days after her discharge. Given the wide use of probiotics, we alert clinicians to consider this microorganism as a causative agent when signs of systemic infection, metabolic compromise, and hemodynamic instability establish after its administration and no pathogens have been identified that could explain the clinical course.