Open AccessHormonal Replacement Therapy in Surgically Induced Menopause: A Prospective Cross Section Study from a Tertiary Care Institution from A Sub-himalayan State
Author(s) -
Jatinder Mokta,
Kiran Mokta,
Arjun Tandon,
Renuka Pathania,
Aniketa Sharma,
M. Praveen Raj,
Akshit Negi,
Arnav Mokta,
. Ramesh
Publication year - 2021
Publication title -
advances in bioscience and clinical medicine
Language(s) - English
Resource type - Journals
ISSN - 2203-1413
DOI - 10.7575/aiac.abcmed.v.9n.3p.10
Subject(s) - medicine , menopause , vasomotor , surgical menopause , osteoporosis , prospective cohort study , hormone replacement therapy (female to male) , oophorectomy , estrogen , hysterectomy , obstetrics , gynecology , physical therapy , pediatrics , surgery , testosterone (patch)
Background: Early surgical menopause increases risk of cardiovascular disease, osteoporosis, fracture, cognitive impairment and sexual dysfunction than women with late menopause. Estrogen therapy (ET) remains the most effective therapy for vasomotor symptoms related to surgically induced menopause. Meterials and Methods: It was a prospective cross-section study. Result: Amongst 255 symptomatic women, 163 (63.92%) women had severe vasomotor symptoms and 54 (33.12% of 163 women) of them had very incapacitating symptoms with marked reduction in their quality of life. 59 (23.13%) women had moderate symptoms with mild disturbances in their sleep while 33 (12.94%) women had only mild symptoms. Conclusion: It is agreed that women who undergo bilateral oophorectomy before the onset of natural menopause should be considered for estrogen therapy for the management of vasomotor symptoms until the average age of natural menopause.