Open AccessCurrent Canadian And American Experiences In The Treatment Of Acute Ischemic Stroke
Author(s) -
Parviz Dolati
Publication year - 2017
Publication title -
advances in bioscience and clinical medicine
Language(s) - English
Resource type - Journals
ISSN - 2203-1413
DOI - 10.7575/aiac.abcmed.ca1.44
Subject(s) - medicine , thrombolysis , stroke (engine) , revascularization , randomized controlled trial , acute stroke , clinical trial , occlusion , endovascular treatment , intensive care medicine , emergency medicine , tissue plasminogen activator , surgery , myocardial infarction , mechanical engineering , engineering , aneurysm
Stroke remains one of the main public health issues worldwide. It is the third leading cause of death in the United States, with more than 200,000 people dying from strokes each year. Approximately 80% of all acute ischemic strokes are due to intracranial artery occlusion, most commonly thromboembolic clot occlusion. Revascularization of occluded territories is the cornerstone of acute ischemic stroke and Thrombolysis for ischemic stroke has been systematically studied in large randomized trials only since the 1990s. To date, thrombolytic therapy for ischemic stroke has been investigated in 21 randomized controlled clinical trials enrolling more than 7,000 patients. The advent of modern imaging and endovascular tools and technologyhas revolutionized treatment of stroke. In this talk, I will review current clinical trials published in The NEJM (ESCAPE, MR Clean, EXTENDED IA, ….) regarding superiority of the endovascular treatments, especially, the stent retrievers, over Iv tPA. I will also go over all endovascular techniques used in the endovascular treatment of acute stroke using my Canadian and American experiences